姓 名：王轲
性 别：男
职 称：研究员，博士生/硕士生导师
所在系别：作物遗传育种系
电 话：010-82105173
电子邮箱：wangke03@caas.cn
◆个人简历（学习/访学/工作简历）
2002.09-2006.07： 临沂大学，生物科学专业，理学学士；
2006.09- 2011.07： 首都师范大学，遗传学专业，理学博士；
2011.07-至今：中国农业科学院作物科学研究所 研究员，博士生导师。
◆研究领域
主要研究方向是小麦遗传转化新技术、基因编辑及小麦营养品质改良。
◆荣誉称号及社会兼职
1. 阿里巴巴育种人才青年科学家，2022；
2. Frontiers in plant science编委，2021。
◆科研项目
1. 利用CRISPR/Cas9创制春小麦单倍体诱导系和优质种质资源材料，2. 宁夏回族自治区科学技术厅重点研发计划，64万元，2022-2025，课题主持人。
2. 小麦再生基因TaCB1在遗传转化中的功能鉴定及分子机理解析，国家自然科学基金面上项目，58万元，2020-2023，课题主持人。
3. 小麦遗传转化相关新技术研究，国家转基因专项，45万元，2016-2020，子课题主持人
4. 小麦TaVIP2基因的克隆、功能鉴定及分子机理研究，国家自然科学基金面上项目，26万元，2015-2017，课题主持人。
◆授权专利
1. 王轲，刘会云，叶兴国，王坤扬，伍小波，杜丽璞，李婕琳，李欣，李仕金。一种表达载体及其在制备转基因植物中的应用，ZL201610204910.0，国家发明专利，2020。
2. 王轲，叶兴国，刘会云，王坤杨，杜丽璞，王静，林志珊。小麦TaWOX5基因在提高小麦转化效率中的应用，ZL201710422896.6，国家发明专利，2020。
3. Ye Xingguo, Wang ke, Ishida Yuji, Yanagihara, Chizu, Liu Huiyun, Wang Kunyang, Shi Lei, Du Lipu, Wang Jing, Lin Zhishan. Method for improving transformation efficiency of plant and method for transforming plant，US 11,447,784 B2，美国发明专利，2022。
4. Ye Xingguo, Wang ke, Ishida Yuji, Yanagihara, Chizu, Liu Huiyun, Wang Kunyang, Shi Lei, Du Lipu, Wang Jing, Lin Zhishan. Method for improving transformation efficiency of plant and method for transforming plant，2018280528，澳大利亚发明专利，2022。
◆发表论文
1. Wang K, Shi L, Liang XN, Zhao P, Wang WX, Liu JX, Chang YN, Hiei Y, Yanagihara C, Du LP, Ishida Y, Ye XG. The gene TaWOX5 overcomes genotype dependency in wheat genetic transformation. Nature Plants, 2022, 8:110-117.
2. Cheng JY, Hill C, Yong Han Y, He TH, Ye XG, Shabala S, Guo GG, Zhou MX, Wang K, Li CD, New semi-dwarfing alleles with increased coleoptilelength by gene editing ofgibberellin 3-oxidase 1usingCRISPR-Cas9 in barley (Hordeum vulgare L.). Plant Biotechnology Journal, 2023, 21:806–818.
3. Zhu YW, Lin YR, Fan YJ, Wang YW, Li PF, Xiong J, He YH, Cheng SF, Ye XG, Wang F, Goodrich J, Zhu JK, Wang K, Zhang CJ. CRISPR/Cas9-mediated restoration of Tamyb10 to create pre-harvest sprouting-resistant red wheat, Plant Biotechnology Journal, 2023, 21:665–667 IF2022=13.8
4. Qu G, Wang K, Mu JY, Zhuo JH, Wang XY, Li SS, Ye XG, Li YX, Yan YM, Li XH. Identifying cis-Acting Elements Associated with the High Activity and Endosperm Specificity of the Promoters of Genes Encoding Low-Molecular-Weight Glutenin Subunits in Common Wheat (Triticum aestivum) J. Agric. Food Chem. 2023, 71, 17432−17441.
5. Zhuo JH, Wang K, Wang N, Xing CH, Peng D, Wang XY, Qu G, Kang CY, Ye XG, Li YX, Yan YM, L XH. Pericarp starch metabolism is associated with caryopsis development and endosperm starch accumulation in common wheat. Plant Science, 2023, 330: 111622.
6. Tang HL, Qiu YL, Wang WX, Yu M, Chang YN, Du LP, Lin ZS, Wang K, Ye XG. Development of a haploid inducer by editing HvMTL in barley. Journal of Genetics and Genomics，2023, 50: 366-369.
7. Wang WX, Huang PP, Dai WS, Tang HL, Qiu YL, Chang YN, Han ZY, Li X, Du LP, Ye XG, Zou C, Wang K. Application of Nicotinamide to Culture Medium Improves the Efficiency of Genome Editing in Hexaploid Wheat. International Journal of Molecular Sciences, 2023, 24: 4416.
8. Hu JX, Yu M, Chang YN, Tang HL, Wang WX, Du LP, Wang K, Yan YM, Ye XG. Functional analysis of TaPDI genes on storage protein accumulation by CRISPR/Cas9 edited wheat mutants. International Journal of Biological Macromolecules, 2022, 196: 131-143.
9. Zang YM, Gong Q, Xu YH, Liu HY, Bai H, Li N, Du LP, Ye XG, Lan CX, Wang K. Production of conjoined transgenic and edited barley and wheat plants for Nud genes using the CRISPR/SpCas9 System. Frontiers in Genetics, 2022, 13: 873850.
10. Qiu YL, Chen HQ, Zhang SX, Wang J, Du LP, Wang K, Ye XG. Development of a wheat material with improved bread-making quality by overexpressing HMW-GS 1Slx2.3* from Aegilops longissima. The Crop Journal, 2022, 10:1717-1726.
11. Tang HL, Liu HY, Zhou Y, Liu HW, Du LP, Wang K, Ye XG. Fertility recovery of wheat male sterility controlled by Ms2 using CRISPR/Cas9. Plant Biotechnology Journal, 2021, 19: 224–226.
12. Chen HQ, Li SJ, Liu YW, Liu JX, Ma XL, Du LP, Wang K, Ye XG. Effects of 1Dy12 subunit silencing on protein body accumulation in seeds and flour-processing quality in a common wheat somatic variation line. Food Chemistry, 2021, 335: 127663.
13. Liu HY, Wang K, Jia ZM, Gong Q, Lin ZS, Lipu Du LP, Pei XW, Ye XG. Efficient induction of haploid plants in wheat by editing of TaMTL using an optimized Agrobacterium-mediated CRISPR system. Journal of Experimental Botany, 2020, 71:1337–1349.
14. Liu HY, Wang K, Tang HL, Gong Q, Du LP, Pei XW, Ye XG. CRISPR/Cas9 editing of wheat TaQ genes alters spike morphogenesis and grain threshability. Journal of Genetics and Genomics, 2020, 47: 563-575.
15. Liang QJ, Wang K, Sharifula I, Ye XG, Zhang CY. Folate content and retention in wheat grains and wheat-based foods: Effects of storage, processing, and cooking methods. Food Chemistry, 2020, 333: 127459.
16. Wang K, Gong Q, Ye XG. Recent developments and applications of genetic transformation and genome editing technologies in wheat. Theoretical and Applied Genetics, 2020, 133:1603-1622.
17. Riaz B, Chen HQ, Wang J, Du LP, Wang K, Ye XG. Overexpression of Maize ZmC1 and ZmR Transcription Factors in Wheat Regulates Anthocyanin Biosynthesis in a Tissue-Specific Manner. International Journal of Molecular Sciences, 2019, 20, 5806.
18. Liang QJ, Wang K, Liu XN, Riaz B, Jiang L, Wan X, Ye XG, Zhang CY. Improved folate accumulation in genetically modified maize and wheat. Journal of Experimental Botany, 2019, 70(5): 1539-1551.
19. Wang K, Riaz B, Ye XG. Wheat genome editing expedited by efficient transformation techniques: Progress and perspectives, Crop Journal, 2018, 6(1): 22-31.
Wang K, Liu HY, Du LP, Ye XG. Generation of marker-free transgenic hexaploid wheat via an Agrobacterium-mediated co-transformation strategy in commercial Chinese wheat varieties, Plant Biotechnology Journal, 2017, 15(5): 614-623.
